A tutorial on receptor binding assays used in bioanalysis. Both scintillation proximity assays and measurements based on fluorescence polarization are discussed. This page also features a good bibliography on related resources.The website is available here .
This site contains an article that describes the use of surface plasmon resonance (SPR) spectroscopy to monitor real-time protein binding with fullerenes and carbon nanotubes. The introductory section provides a brief description of SPR and how it works. It next talks about the features of the Texas Instrument's SPR, known as Speetra, which is…
This site produced by the Dolan DNA Learning Center of the Cold Springs Harbor Laboratory contains a number of high quality animations that explain processes important in bioanalytical chemistry. For example, one animation illustrates the process of Sanger sequencing and another explains what Gene Chips are and how they work. PCR, gel electrophoresis, cloning, model organisms…
US Environmental Protection Agency site that explains GC for those interested in environmental analysis. Assumes some user background in the field. Includes a partial list of EPA Field Methods that utilize GC which may be helpful to those interested in regulatory protocols.
The website is available here .
Further Analytical Methods developed by the Environmental…
Kinetic Capillary Electrophoresis is a family of methods for studying binding of biopolymers, measuring rate constants, binding constants, and in some cases providing mechanistic details. This Online Article is a presentation by the originators of this family of techniques ready for classroom or independent use.The website is available here .
This is an experiment showing the application of affinity chromatography to the separation of albumin from horse serum. A brief introduction of affinity chromatography and how it is being used in this specific experiment is given. This appears to be a good experiment to show the advantages of affinity chromatography in separating specific proteins from a…
This site is one of many on \\\"nanoHUB.org\\\" which highlights availability of on-line simulations. This particular one provides a video of a research seminar on the topic of micromechanical biosensors focusing on aptamer-based receptor molecules. The quality of the graphics in the video is not high - mainly, the smallness of the visuals makes it difficult…
The site provides introductory information related to optical microscopy. Among the topics addressed are resolution, numerical aperture, depth of field, field of view, illumination and the useful magnification range. A section on fluorescence microscopy is also included. Interactive video is used to demonstrate concepts in some cases. Researchers and educators interested in a brief overview of…
The site contains a set of experimental and teaching modules that cover the fundamentals, history and practice of microscopy. Modules on microscopy, FRET, FRAP and Quantitative Multidimensional Microscopy will be of interest to chemists and biologists. Several include great graphics that would be helpful additions for instrumental analysis lectures.
The website is available here .
This site contains a thorough overview of the fundamentals of antibodies. The site starts with an introduction to antigens and antibodies, antibody production and titer including practical information.The website is available here .